Description
Enfiera 100 Injection is a rituximab-based medicine used to manage certain cancers and autoimmune disorders. It contains rituximab 100 mg, a monoclonal antibody that targets a protein called CD20 found on certain B cells.
Enfiera 100 mg Injection is used for conditions such as non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris. Its use depends on the patient’s condition and treatment plan recommended by a doctor.
Enfiera 100 Injection is given directly into a vein through an intravenous (IV) infusion by a doctor or trained healthcare professional. Rituximab can cause infusion-related reactions and may increase the risk of infections. Patients are therefore monitored during treatment. Tell your doctor about any existing infection, previous hepatitis B infection, heart problems, or breathing difficulties before starting treatment.
What Is Enfiera 100 mg Injection?
Enfiera 100 mg Injection is a prescription medicine used to treat certain cancers and autoimmune conditions. It contains rituximab, which belongs to a group of medicines called anti-CD20 monoclonal antibodies. This medicine is given as an intravenous (IV) infusion by a doctor or trained healthcare professional and should not be self-administered.
Rituximab works by targeting a protein called CD20, which is found on B cells, a type of white blood cell. By reducing these B cells, Enfiera 100 mg Injection can help control abnormal cell growth in certain blood cancers and reduce harmful immune activity in some autoimmune diseases.
The dose and treatment schedule depend on the condition being treated and the patient’s overall health. Enfiera is marketed by Zydus Lifesciences.
Enfiera 100 mg Injection Composition
Each Enfiera 100mg Injection contains rituximab 100 mg as its active ingredient. Product information also lists excipients such as sodium chloride, trisodium citrate dihydrate and polysorbate 80. The product is supplied as a 10 mL vial. Rituximab is a biologic medicine belonging to the class of anti-CD20 monoclonal antibodies.
How Does Enfiera 100 mg Injection Work?
Enfiera 100 mg Injection works by targeting specific B cells in the immune system. It contains rituximab, which attaches to a protein called CD20 found on certain B cells, a type of white blood cell. This helps the immune system remove these cells from the body.
In certain blood cancers, this action helps reduce abnormal B cells. In autoimmune conditions, reducing B cells can help lower unwanted immune activity and inflammation. Since B cells also support normal immune function, treatment may temporarily increase the risk of infections.
For this reason, doctors may perform blood tests and monitor patients during treatment. Enfiera is given as an intravenous infusion under medical supervision.
Uses of Enfiera 100 mg Injection
Enfiera 100 mg Injection contains rituximab and may be used to treat certain cancers and autoimmune conditions. Its uses include:
- Non-Hodgkin lymphoma (NHL): Certain B-cell lymphomas may be treated with rituximab alone or in combination with other medicines.
- Chronic lymphocytic leukemia (CLL): Rituximab may form part of treatment for certain patients with B-cell CLL.
- Rheumatoid arthritis: It may be used for moderate-to-severe rheumatoid arthritis in combination with other appropriate therapy.
- Granulomatosis with polyangiitis (GPA): Rituximab can be used to reduce abnormal immune activity associated with this condition.
- Microscopic polyangiitis (MPA): It may be used as part of treatment for this type of blood-vessel inflammation.
- Pemphigus vulgaris: Rituximab may be used for certain patients with this autoimmune blistering disorder.
Strengths and Substitutes
Enfiera 500 Injection
Maball 100 Injection
Mabtas 500 Injection
Mabtas 100 Infusion
Maball 500 Injection
Dosage of Enfiera 100 mg Injection
The Enfiera 100 mg Injection dosage depends on the disease being treated and the patient’s health condition. The doctor decides the right dose and treatment schedule based on individual needs and other medicines being used.
Enfiera 100 mg is given as an intravenous infusion (IV) by a doctor or trained healthcare professional. Other medicines may be given before the infusion to help reduce possible reactions.
Do not use or change the dose of Enfiera 100 mg on your own. If you miss an appointment, contact your doctor to schedule another dose.
Side Effects of Enfiera 100 mg Injection
Enfiera 100 mg Injection may cause some side effects, but not everyone experiences them. Common side effects may include:
- Headache
- Fever or chills
- Nausea
- Tiredness or weakness
- Skin rash or itching
- Swelling
- Diarrhea
- Infections
- Hair loss
- Changes in blood cell levels
Some patients may experience infusion-related reactions while receiving Enfiera or shortly after treatment. These may include fever, chills, headache, changes in blood pressure, breathing problems, skin rash, nausea, or chest discomfort.
Tell your doctor immediately if you experience severe breathing problems, swelling of the face or throat, chest pain, or a serious allergic reaction during or after infusion.
Enfiera may also increase the risk of infections and can reactivate hepatitis B in some patients. Your doctor may recommend appropriate tests and monitoring before and during treatment.
Precautions and Warnings
Before using Enfiera 100 mg Injection, share your complete medical history and current medicines with your healthcare professional.
- Avoid treatment if you have an active infection or have recently had a serious infection.
- Previous hepatitis B infection is important because it may become active again during treatment.
- Heart problems or breathing difficulties may require special monitoring.
- Blood tests and other medical checks may be needed before and during treatment.
- Discuss any planned vaccinations before starting treatment.
- Pregnancy, pregnancy planning, and breastfeeding should be discussed before treatment.
- Rituximab can affect the immune system, so monitor for signs of infection during and after treatment.
- Enfiera should not be used in patients with a serious allergy to rituximab or any ingredient in this medicine.
Drug Interactions of Enfiera 100 mg Injection
Tell your doctor about all medicines, vitamins, supplements, and herbal products you are taking before starting Enfiera 100 mg Injection.
Medicines that affect your immune system may increase the risk of infections when used with Enfiera. Vaccines may also need special consideration during rituximab treatment.
Your doctor will review your medicines to help prevent unwanted interactions. Do not start, stop, or change any medicine without consulting your doctor.
Enfiera 100 mg Injection Storage
Store Enfiera 100 mg Injection in a refrigerator at 2°C to 8°C. Do not freeze it. Keep it in its original packaging and protect it from inappropriate storage conditions. Keep medicines out of reach of children.
Buy Enfiera 100 mg Injection Online
If you want to buy Enfiera 100 Injection online choose a licensed and trusted pharmacy that requires a valid prescription. Before placing an order check the medicine name strength pack size expiry date and packaging carefully. Enfiera must be administered by a trained healthcare professional. Buying it online does not replace a doctor’s consultation or proper medical supervision.
